Staphylococcus aureus

Data Downloaded from EBI:

-Would not let me right click and copy the file 1 ans file 2 on my mac.

Project Focus:

I will be researching Staphylococcus aureus and how this bacteria is related to and if it actually causes endocarditis. I will be looking at a study that showed this infection as a health-care associated infection and comparing it to infections outside of a hospital setting. I will be using this paper for research: along with others. I will be looking at whole-genome sequencing of bloodstream S. Aureus.

Endocarditis Strains 1-4

Strain 1: SAMEA104137068

  • File 1:
  • File 2:

Strain 2: SAMEA104137069

  • File 1:
  • File 2:

Strain 3: SAMEA104137070

  • File 1:
  • File 2:

Strain 4: SAMEA104137071

  • File 1:
  • File 2:


Human-To-Bovine (

CC8 Strains 5-7

Strain 5: SAMN06320931

  • File 1:
  • File 2:

Strain 6: SAMN06320930

  • File 1:
  • File 2:

Strain 7: SAMN06320904

  • File 1:
  • File 2:


Poster Content


  • S. aureus is a member of the normal flora in the body, is a coccal (round) shaped bacteria that is Gram-Positive
  • Found in the Resp. tract, nose, and skin
  • Strains are not always pathogenic, if they are they are the common cause of skin infections, abscesses and resp infections.
  • The isolates can cause invasive disease, but it is unknown if some isolates are more likely to cause severe infections then others (EBI reference)
  • Pathogenic strains promote infections by producing virulence factors such as protein toxins and the expression of a cell-surface protein that binds and inactivates antibodies
  • Common antibiotic resistant strain of S. aureus is MRSA
  • No approved vaccine
  • 20-30% of the human population are long term carriers
  • S. aureus is most common causes of bacteria and infective Endocarditis
  • Leading cause of bloodstream infections
  • W/o antibiotics=fatality rate of 80%, With= 15-50% depending on age and health (Reference to info above)

Reference Genome:

ASM900v1 Ref-1

ASM958v1 Ref-2

ASM964v1 Ref-3 (didn’t download yet)



Screen Shot 2018-04-24 at 4.09.07 PM.png

Screen Shot 2018-04-24 at 9.03.57 AM


Screen Shot 2018-04-17 at 8.52.53 AM.png





Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s